Antibiotic sensitivity of gonococci and treatment of gonorrhoea in Uganda.

VENEREAL disease, especially gonorrhoea, is of very common occurrence among students of Makerere University College, in Kampala, Uganda (Arya and Bennett; 1967, 1968), and this provides an excellent opportunity for the study of the treatment of gonorrhoea. Most patients are seen by one doctor, and almost all can be followed up until it is clear that they are either free from infection or have been re-infected. Furthermore they are prepared to be frank about reexposure, making it relatively easy to distinguish true failures of treatment from re-infection. This study was aimed at determining the minimum useful dose of the various preparations ofpenicillin or tetracycline available to us for the treatment of acute gonococcal urethritis in males. The minimum inhibitory concentration (M.I.C.) of penicillin was determined for all strains of gonococci isolated.